Bielawska, Alicja: search on Z-Library

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1

Synthesis of unsymmetrical disulfanes bearing 1,2,4-triazine scaffold and their in vitro screening towards anti-breast cancer activity

Branowska, Danuta, Ławecka, Justyna, Sobiczewski, Mariusz, Karczmarzyk, Zbigniew, Wysocki, Waldemar, Wolińska, Ewa, Olender, Ewa, Mirosław, Barbara, Perzyna, Alicja, Bielawska, Anna, Bielawski, Krzysz

Journal:

Monatshefte für Chemie - Chemical Monthly

Year:

2018

Language:

english

File:

PDF, 1.07 MB

english, 2018

2

ChemInform Abstract: A Facile Regioselective Synthesis of Sphingosine 1-Phosphate (IV) and Ceramide 1-Phosphate (VIII)

Zdzislaw M. Szulc, Yusuf A. Hannun, Alicja Bielawska

Journal:

Year:

2000

File:

PDF, 28 KB

2000

3

Novel analogs of d-e-MAPP and B13. Part 2: Signature effects on bioactive sphingolipids

Alicja Bielawska, Jacek Bielawski, Zdzislaw M. Szulc, Nalini Mayroo, Xiang Liu, AiPing Bai, Saeed Elojeimy, Barbara Rembiesa, Jason Pierce, James S. Norris, Yusuf A. Hannun

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.43 MB

english, 2008

4

Lipid Channels: Positive and Negative Cooperativity and Regulation by Proteins

Ganesan, Vidyaramanan, Perera, Meenu N., Siskind, Leah, Szulc, Zdzislaw, Bielawska, Alicja, Colombini, Marco

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 37 KB

english, 2009

5

Cationic ceramides and analogues, LCL30 and LCL85, as adjuvants to photodynamic therapy of tumors

Korbelik, Mladen, Zhang, Wei, Saw, Kyi Min, Szulc, Zdzislaw M., Bielawska, Alicja, Separovic, Duska

Journal:

Journal of Photochemistry and Photobiology B: Biology

Year:

2013

Language:

english

File:

PDF, 517 KB

english, 2013

6

Erratum to “Novel analogs of d-e-MAPP and B13. Part 1: Synthesis and evaluation as potential anticancer agents” [Bioorg. Med. Chem. 16 (2008) 1015–1031]

Zdzislaw M. Szulc, Nalini Mayroo, AiPing Bai, Jacek Bielawski, Xiang Liu, James S. Norris, Yusuf A. Hannun, Alicja Bielawska

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 59 KB

english, 2008

7

Novel analogs of d-e-MAPP and B13. Part 1: Synthesis and evaluation as potential anticancer agents

Zdzislaw M. Szulc, Nalini Mayroo, AiPing Bai, Jacek Bielawski, Xiang Liu, James S. Norris, Yusuf A. Hannun, Alicja Bielawska

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 582 KB

english, 2008

8

Differential regulation of acid sphingomyelinase in macrophages stimulated with oxidized low-density lipoprotein (LDL) and oxidized LDL immune complexes: role in phagocytosis and cytokine release

Jean-Philip Truman, Mohammed M. Al Gadban, Kent J. Smith, Russell W. Jenkins, Nalini Mayroo, Gabriel Virella, Maria F. Lopes-Virella, Alicja Bielawska, Yusuf A. Hannun, Samar M. Hammad

Journal:

Year:

2012

Language:

english

File:

PDF, 1.19 MB

english, 2012

9

Cognitive and social function in girls with congenital adrenal hyperplasia — Influence of prenatally administered dexamethasone

Maryniak, Agnieszka, Ginalska-Malinowska, Maria, Bielawska, Alicja, Ondruch, Agnieszka

Journal:

Child Neuropsychology

Year:

2014

Language:

english

File:

PDF, 145 KB

english, 2014

10

Erratum to “Novel analogs of d-e-MAPP and B13. Part 2: Signature effects on bioactive sphingolipids” [Bioorg. Med. Chem. 16 (2008) 1032–1045]

Alicja Bielawska, Jacek Bielawski, Zdzislaw M. Szulc, Nalini Mayroo, Xiang Liu, AiPing Bai, Saeed Elojeimy, Barbara Rembiesa, Jason Pierce, James S. Norris, Yusuf A. Hannun

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 71 KB

english, 2008

11

Enhanced killing of SCC17B human head and neck squamous cell carcinoma cells after photodynamic therapy plus fenretinide via the de novo sphingolipid biosynthesis pathway and apoptosis

Boppana, Nithin, Stochaj, Ursula, Kodiha, Mohamed, Bielawska, Alicja, Bielawski, Jacek, Pierce, Jason, Korbelik, Mladen, Separovic, Duska

Journal:

International Journal of Oncology

Year:

2015

Language:

english

File:

PDF, 551 KB

english, 2015

12

Role for Ceramide as an Endogenous Mediator of Fas-Induced Cytotoxicity

Clifford G. Tepper, Supriya Jayadev, Bin Liu, Alicja Bielawska, Robert Wolff, Shin Yonehara, Yusuf A. Hannun and Michael F. Seldin

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.19 MB

english, 1995

13

FcγRII Activation Induces Cell Surface Ceramide Production which Participates in the Assembly of the Receptor Signaling Complex

Korzeniowski, Marek, Shakor, Abo, Makowska, Agnieszka, Drzewiecka, Anna, Bielawska, Alicja, Kwiatkowska, Katarzyna, Sobota, Andrzej

Journal:

Cellular Physiology and Biochemistry

Year:

2007

Language:

english

File:

PDF, 2.85 MB

english, 2007

14

Interaction of acid ceramidase inhibitor LCL521 with tumor response to photodynamic therapy and photodynamic therapy-generated vaccine

Korbelik, Mladen, Banáth, Judit, Zhang, Wei, Min Saw, Kyi, Szulc, Zdzislaw M., Bielawska, Alicja, Separovic, Duska

Journal:

International Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 465 KB

english, 2016

15

Targeting acid sphingomyelinase with anti-angiogenic chemotherapy

Jacobi, Jeanna, García-Barros, Mónica, Rao, Shyam, Rotolo, Jimmy A, Thompson, Chris, Mizrachi, Aviram, Feldman, Regina, Manova, Katia, Bielawska, Alicja, Bielawska, Jacek, Fuks, Zvi, Kolesnick, Richar

Journal:

Cellular Signalling

Year:

2016

Language:

english

File:

PDF, 860 KB

english, 2016

16

Tailoring structure–function and targeting properties of ceramides by site-specific cationization

Zdzislaw M. Szulc, Jacek Bielawski, Hanna Gracz, Marietta Gustilo, Nalini Mayroo, Yusuf A. Hannun, Lina M. Obeid, Alicja Bielawska

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 589 KB

english, 2006

17

Lysosomotropic acid ceramidase inhibitor induces apoptosis in prostate cancer cells

David H. Holman, Lorianne S. Turner, Ahmed El-Zawahry, Saeed Elojeimy, Xiang Liu, Jacek Bielawski, Zdzislaw M. Szulc, Kristi Norris, Youssef H. Zeidan, Yusuf A. Hannun, Alicja Bielawska, James S. Norr

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 660 KB

english, 2008

18

Inhibition of growth and telomerase activity by novel cationic ceramide analogs with high solubility in human head and neck squamous cell carcinoma cells

Michael J. Rossi, Kamala Sundararaj, Serap Koybasi, Monique S. Phillips, Zdzislaw M. Szulc, Alicja Bielawska, Terry A. Day, Lina M. Obeid, Yusuf A. Hannun, Besim Ogretmen

Journal:

Otolaryngology - Head and Neck Surgery

Year:

2005

Language:

english

File:

PDF, 306 KB

english, 2005

19

Bax and Bcl-xL exert their regulation on different sites of the ceramide channel

Perera, Meenu N., Lin, Shang H., Peterson, Yuri K., Bielawska, Alicja, Szulc, Zdzislaw M., Bittman, Robert, Colombini, Marco

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.75 MB

english, 2012

20

Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner

Tirodkar, Tejas S., Lu, Ping, Bai, Aiping, Scheffel, Matthew J., Gencer, Salih, Garrett-Mayer, Elizabeth, Bielawska, Alicja, Ogretmen, Besim, Voelkel-Johnson, Christina

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 1.88 MB

english, 2015

21

C16-Ceramide Analog Combined with Pc 4 Photodynamic Therapy Evokes Enhanced Total Ceramide Accumulation, Promotion of DEVDase Activation in the Absence of Apoptosis, and Augmented Overall Cell Killing

Separovic, Duska, Saad, Ziad H., Edwin, Ethan A., Bielawski, Jacek, Pierce, Jason S., Buren, Eric Van, Bielawska, Alicja

Journal:

Journal of Lipids

Year:

2011

Language:

english

File:

PDF, 2.12 MB

english, 2011

22

The functional effects of acid ceramidase over-expression in prostate cancer progression and resistance to chemotherapy

Saad, Antonio F., Meacham, William D., Bai, Aiping, Anelli, Viviane, Anelli, Viviane, Mahdy, Ayman E.M., Turner, Lorianne S., Cheng, Joe, Bielawska, Alicja, Bielawski, Jacek, Keane, Thomas E., Obeid,

Journal:

Cancer Biology & Therapy

Year:

2007

Language:

english

File:

PDF, 600 KB

english, 2007

23

Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis

Pulkoski-Gross, Michael J., Uys, Joachim D., Orr-Gandy, K. Alexa, Coant, Nicolas, Bialkowska, Agnieszka B., Szulc, Zdzislaw M., Bai, Aiping, Bielawska, Alicja, Townsend, Danyelle M., Hannun, Yusuf A.,

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2017

Language:

english

File:

PDF, 1.20 MB

english, 2017

24

Dietary palmitate cooperates with Src kinase to promote prostate tumor progression

Kim, Sungjin, Yang, Xiangkun, Yin, Amelia, Zha, Junyi, Beharry, Zanna, Bai, Aiping, Bielawska, Alicja, Bartlett, Michael G., Yin, Hang, Cai, Houjian

Journal:

Year:

2019

File:

PDF, 2.56 MB

2019

25

The ceramide analog, B13, induces apoptosis in prostate cancer cell lines and inhibits tumor growth in prostate cancer xenografts

Leigh Samsel, Grazyna Zaidel, Honesty M. Drumgoole, Danijela Jelovac, Cinthia Drachenberg, Juong G. Rhee, Angela M.H. Brodie, Alicja Bielawska, Miriam J. Smyth

Journal:

Year:

2004

Language:

english

File:

PDF, 282 KB

english, 2004

26

De novo N-palmitoylsphingosine synthesis is the major biochemical mechanism of ceramide accumulation following p53 up-regulation

Shoghag Panjarian, Lina Kozhaya, Sawsan Arayssi, Maisaa Yehia, Jacek Bielawski, Alicja Bielawska, Julnar Usta, Yusuf A. Hannun, Lina M. Obeid, Ghassan S. Dbaibo

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2008

Language:

english

File:

PDF, 449 KB

english, 2008

27

Regulation of the sphingosine-recycling pathway for ceramide generation by oxidative stress, and its role in controlling c-Myc/Max function

Sultan, Iyad, Senkal, Can E., Ponnusamy, Suriyan, Bielawski, Jacek, Szulc, Zdzislaw, Bielawska, Alicja, Hannun, Yusuf A., Ogretmen, Besim

Journal:

Biochemical Journal

Year:

2006

Language:

english

File:

PDF, 514 KB

english, 2006

28

Ceramide channel: Structural basis for selective membrane targeting

Perera, Meenu N., Ganesan, Vidyaramanan, Siskind, Leah J., Szulc, Zdzislaw M., Bielawska, Alicja, Bittman, Robert, Colombini, Marco

Journal:

Chemistry and Physics of Lipids

Year:

2015

Language:

english

File:

PDF, 889 KB

english, 2015

29

Bax, Bcl-xl Exert their Regulation on Different Sites on the Ceramide Channel

Perera, Meenu N., Bielawska, Alicja, Szulc, Zdzislaw M., Bittman, Robert, Colombini, Marco

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 32 KB

english, 2011

30

Determination of Ceramides and Diglycerides by the Diglyceride Kinase Assay

Alicja Bielawska, David K. Perry, Yusuf A. Hannun

Journal:

Analytical Biochemistry

Year:

2001

Language:

english

File:

PDF, 165 KB

english, 2001

31

Ceramide Kinase Mediates Cytokine- and Calcium Ionophore-induced Arachidonic Acid Release

Pettus, Benjamin J., Bielawska, Alicja, Spiegel, Sarah, Roddy, Patrick, Hannun, Yusuf A., Chalfant, Charles E.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 702 KB

english, 2003

32

Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry

Jacek Bielawski, Zdzislaw M. Szulc, Yusuf A. Hannun, Alicja Bielawska

Journal:

Year:

2006

Language:

english

File:

PDF, 300 KB

english, 2006

33

Dietary glucosylceramides suppress tumor growth in a mouse xenograft model of head and neck squamous cell carcinoma by the inhibition of angiogenesis through an increase in ceramide

Yazama, Hiroaki, Kitatani, Kazuyuki, Fujiwara, Kazunori, Kato, Misaki, Hashimoto-Nishimura, Mayumi, Kawamoto, Katsuyuki, Hasegawa, Kensaku, Kitano, Hiroya, Bielawska, Alicja, Bielawski, Jacek, Okazaki

Journal:

International Journal of Clinical Oncology

Year:

2015

Language:

english

File:

PDF, 1.77 MB

english, 2015

34

Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression

Paschall, Amy V, Zimmerman, Mary A, Torres, Christina M, Yang, Dafeng, Chen, May R, Li, Xia, Bieberich, Erhard, Bai, Aiping, Bielawski, Jacek, Bielawska, Alicja, Liu, Kebin

Journal:

Year:

2014

Language:

english

File:

PDF, 714 KB

english, 2014

35

A two-step chemical and circular dichroic method for assigning the absolute configurations of sphingosines

Verena Dirsch, Justin Frederico, Ning Zhao, Guolin Cai, Yanqui Chen, Satyanarayana Vunnam, Joshua Odingo, Hyan Pu, Koji Nakanishi, Nina Berova, Dennis Liotta, Alicja Bielawska, Yusuf Hannun

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 271 KB

english, 1995

36

2′-Hydroxy C16-Ceramide Induces Apoptosis-Associated Proteomic Changes in C6 Glioma Cells

Kota, Venkatesh, Dhople, Vishnu M., Fullbright, George, Smythe, Nancy M., Szulc, Zdzislaw M., Bielawska, Alicja, Hama, Hiroko

Journal:

Journal of Proteome Research

Year:

2013

Language:

english

File:

PDF, 17.80 MB

english, 2013

37

INHIBITION OF ACID CERAMIDASE SENSITIZES PROSTATE CANCER TO RADIATION THERAPY BOTH IN VITRO AND IN VIVO

Mahdy, Ayman, Liu, Xiang, Li, Jun, Elojeimy, Saeed, Cheng, Joe, Turner, Lorianne, Bai, Aiping, El-Zawahry, Ahmed M, Bielawska, Alicja, Hannun, Yusuf A, Keane, Thomas E, Taha, Mohammed I, Hammouda, His

Journal:

The Journal of Urology

Year:

2008

Language:

english

File:

PDF, 229 KB

english, 2008

38

Mechanistic insights into ceramidase inhibitor LCL521-enhanced tumor cell killing by photodynamic and thermal ablation therapies

Korbelik, Mladen, Zhao, Jianhua, Zeng, Haishan, Bielawska, Alicja, Szulc, Zdzislaw M.

Journal:

Photochemical & Photobiological Sciences

Year:

2020

File:

PDF, 1.67 MB

2020

39

Modulation of cell growth and differentiation by ceramide

Alicja Bielawska, Corinne M. Linardic, Yusuf A. Hannun

Journal:

Year:

1992

Language:

english

File:

PDF, 287 KB

english, 1992

40

Anti-ceramidase LCL385 acutely reduces BCL-2 expression in the hippocampus but is not associated with an increase of learned helplessness in rats

Ziad Nahas, Yan Jiang, Youssef H. Zeidan, Alicja Bielawska, Zdzislaw Szulc, Lindsay DeVane, Peter Kalivas, Yusuf A. Hannun

Journal:

Behavioural Brain Research

Year:

2009

Language:

english

File:

PDF, 254 KB

english, 2009

41

Ceramide and glucosylceramide upregulate expression of the multidrug resistance gene MDR1 in cancer cells

Valérie Gouazé-Andersson, Jing Y. Yu, Adam J. Kreitenberg, Alicja Bielawska, Armando E. Giuliano, Myles C. Cabot

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2007

Language:

english

File:

PDF, 902 KB

english, 2007

42

Dose dependent actions of LCL521 on acid ceramidase and key sphingolipid metabolites

Bai, Aiping, Bielawska, Alicja, Rahmaniyan, Mehrdad, Kraveka, Jacqueline M., Bielawski, Jacek, Hannun, Yusuf A.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 3.85 MB

english, 2018

43

Inhibition of acid ceramidase regulates MHC class II antigen presentation and suppression of autoimmune arthritis

Zhao, Dan, Hajiaghamohseni, Laela M., Liu, Xiang, Szulc, Zdzislaw M., Bai, Aiping, Bielawska, Alicja, Norris, James S., Reddy, Sakamuri V., Hannun, Yusuf A., Haque, Azizul

Journal:

Year:

2020

File:

PDF, 1.68 MB

2020

44

Combining anticancer agents photodynamic therapy and LCL85 leads to distinct changes in the sphingolipid profile, autophagy, caspase-3 activation in the absence of cell death, and long-term sensitization

Duska Separovic, Nicholas Joseph, Paul Breen, Jacek Bielawski, Jason S. Pierce, Eric Van Buren, Gaurav Bhatti, Ziad H. Saad, Aiping Bai, Alicja Bielawska

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 496 KB

english, 2011

45

Synthesis and bioevaluation of ω-N-amino analogs of B13

Aiping Bai, Zdzislaw M. Szulc, Jacek Bielawski, Nalini Mayroo, Xiang Liu, James Norris, Yusuf A. Hannun, Alicja Bielawska

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 524 KB

english, 2009

46

Synthesis, NMR characterization and divergent biological actions of 2′-hydroxy-ceramide/dihydroceramide stereoisomers in MCF7 cells

Zdzislaw M. Szulc, Aiping Bai, Jacek Bielawski, Nalini Mayroo, Doreen E. Miller, Hanna Gracz, Yusuf A. Hannun, Alicja Bielawska

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 904 KB

english, 2010

47

Ceramide channels: Influence of molecular structure on channel formation in membranes

Meenu N. Perera, Vidyaramanan Ganesan, Leah J. Siskind, Zdzislaw M. Szulc, Jacek Bielawski, Alicja Bielawska, Robert Bittman, Marco Colombini

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2012

Language:

english

File:

PDF, 950 KB

english, 2012

48

Acid ceramidase upregulation in prostate cancer: role in tumor development and implications for therapy

Liu, Xiang, Cheng, Joseph C, Turner, Lorianne S, Elojeimy, Saeed, Beckham, Thomas H, Bielawska, Alicja, Keane, Thomas E, Hannun, Yusuf A, Norris, James S

Journal:

Expert Opinion on Therapeutic Targets

Year:

2009

Language:

english

File:

PDF, 692 KB

english, 2009

49

Ring-Chain Tautomerism of Imidazolidine System

Witek, Stanislaw, Bielawska, Alicja, Bielawski, Jacek

Journal:

Year:

1980

Language:

english

File:

PDF, 112 KB

english, 1980

50

A facile regioselective synthesis of sphingosine 1-phosphate and ceramide 1-phosphate

Zdzislaw M Szulc, Yusuf A Hannun, Alicja Bielawska

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 78 KB

english, 2000

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